Тип публикации: статья из журнала
Год издания: 2014
Идентификатор DOI: 10.1007/s10973-013-3578-1
Ключевые слова: Betulin dipropionate, DSC, Enthalpy of fusion, Melting point, Ambient conditions, Arabinogalactan, Fumed silicas, Mechanical activation, Poly vinyl pyrrolidone, Mixtures
Аннотация: Melting of betulin dipropionate (3 beta,28-di-O-propionyl-lup-20(29)-lupene) of high purity (orthorhombic P2(1)2(1)2(1), a = 1.27409(2), b = 1.57316(3), c = 1.59810(3) nm) and its mixtures with four excipients was investigated with DSC and TG. Melting point is 163.6 A degrees C (a dagger(f) H = 33 kJ mol(-1)). Smaller values reported recently were measured for not pure samples. The melt of betulin dipropionate remains glassy under ambient conditions and does not crystallize during the second heating. In mixture with excipients (arabinogalactan, polyethylene glycol, polyvinylpyrrolidone, and fumed silica), the betulin dipropionate loses its crystal structure after mechanical activation.
Издание
Журнал: JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
Выпуск журнала: Vol. 115, Is. 3
Номера страниц: 2521-2525
ISSN журнала: 13886150
Место издания: DORDRECHT
Издатель: SPRINGER
Персоны
- Drebushchak V.A. (Novosibirsk State University)
- Shakhtshneider T.P. (Institute of Solid State Chemistry and Mechanochemistry,SB RAS)
- Drebushchak T.N. (Institute of Solid State Chemistry and Mechanochemistry,SB RAS)
- Mikhailenko M.A. (Institute of Solid State Chemistry and Mechanochemistry,SB RAS)
- Kuznetsova S.A. (Siberian Federal University)
- Malyar J.N. (Institute of Chemistry and Chemical Technology,SB RAS)
Вхождение в базы данных
Информация о публикациях загружается с сайта службы поддержки публикационной активности СФУ. Сообщите, если заметили неточности.