Сибирский федеральный университет

Тип публикации: статья из журнала

Год издания: 2015

Ключевые слова: Radioprotector, ramson, Allium Ursinum, Bog bilberry, Vaccinium uliginosum, mice, x-ray

Аннотация: Radioprotective properties of the products produced from ramson ( Allium Ursinum L.) and bog bilberry ( Vaccinium uliginosum L.) were studied. Mice fed with the dried ramson and the bog bilberry extract were irradiated by X-rays (8 Gray). Strong radioprotective effect of these plant products was registered. The ramson demonstrated more radioprotective effect in comparison with bog bilberry extract. The radioprotective effect of Allium is probably determined by cysteine sulfoxides and their degradation products, such as diallyl disulfide and allyl methyl disulfide. The radioprotectors studied increase minimum parameters of erythropoiesis (red blood cell number and hematocrit) by a factor 1,5. Rapid recovery of the parameter of the platelets number of peripheral blood in all groups in comparison with control was registered. The survival of mice fed with the dried ramson and the bog bilberry extract increased up to 60 and 53%, correspondingly, in comparison with 6,7% in the control group. These substances do not have side effects and contraindications and may be considered as a promising radioprotectors.

Журнал: Химия растительного сырья

Выпуск журнала: № 2

Номера страниц: 253-256

ISSN журнала: 10295151

Место издания: Барнаул

Издатель: федеральное государственное бюджетное образовательное учреждение высшего образования "Алтайский государственный университет"

• Tarabanko Valery E. (Institute of Chemistry and Chemical Technology SB RAS)
• Rodionov Evgeniy T. (LTD «Dikorosy»)
• Toporkova Ludmila B. (Scientific Research Institute of Clinical immunology)
• Muench Sergey (IOANESSI GmbH)
• Orlovskaya Irina A. (Scientific Research Institute of Clinical immunology)

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