The influence of hypokinesia on free calcium cation content in myocytes of rat skeletal muscles and myocardium | Научно-инновационный портал СФУ

The influence of hypokinesia on free calcium cation content in myocytes of rat skeletal muscles and myocardium

Перевод названия: Влияние гиподинамии на содержание свободного Са2+ в миоцитах скелетной мускулатуры и миокарда крыс

Тип публикации: статья из журнала

Год издания: 2010

Идентификатор DOI: 10.1134/S1990747810010137

Ключевые слова: Calcium cations, Cardiac myocytes, Hypokinesia, Membrane microviscosity, Skeletal muscle myocytes, calcium ion, cation, lipid, reduced nicotinamide adenine dinucleotide phosphate, animal cell, animal experiment, animal model, apoptosis, article, calcium cell level, cell function, cell membrane fluidity, controlled study, enzyme activity, heart muscle cell, lipid bilayer, male, membrane structure, muscle fiber membrane, nonhuman, priority journal, protein lipid interaction, rat, skeletal muscle, viscosity, Rattus

Аннотация: The influence of hypokinesia on the content of free Ca2+ and the level of NAD(P)H in myocytes of rat skeletal muscles and myocardium, and microviscosity of myocyte membranes was investigated. It has been found that hypokinesia increased the free Ca2+ content and NAD(P)H level in myocytes of skeletal muscles and myocardium. Alterations of structural- functional properties of membrane that appeared as an increase of membrane fluidity in the regions of lipid bilayer and protein-lipid contact were observed only in skeletal muscles. It was supposed that an increase of calcium cation level in myocytes stimulated the activity of enzymes involved in the apoptosis process that results in the decrease of muscle tissue mass. © 2010 Pleiades Publishing, Ltd.

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Издание

Журнал: Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology

Выпуск журнала: Vol. 4, Is. 1

Номера страниц: 85-89

Авторы

  • Zamay T.N. (Siberian Federal University)
  • Kadkin A.A. (Siberian Federal University)
  • Zamay O.S. (Siberian Federal University)

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