Сибирский федеральный университет

Тип публикации: статья из журнала

Год издания: 2015

Идентификатор DOI: 10.2174/1386207318666150917100257

Ключевые слова: Bioluminescence, bioluminescent toxicity enzymatic assay, immobilization of enzymes, luciferase, total toxicity

Аннотация: This review describes the principle and applications of bioluminescent enzymatic toxicity bioassays. This type of assays uses bacterial coupled enzyme systems: NADH: FMN-oxidoreductase and luciferase to replace living organisms in developing cost-competitive biosensors for environmental, medical and industrial applications. These biosensors instantly signal chemical and biological hazards and allow for detecting a great amount of toxic compounds with advantages associated with fast results, high sensitivity, simplicity, low cost and safety of the procedure.

Журнал: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Выпуск журнала: Vol. 18, Is. 10

Номера страниц: 952-959

ISSN журнала: 13862073

Место издания: SHARJAH

Издатель: BENTHAM SCIENCE PUBL LTD

• Kratasyuk V.A. (Photobiology Laboratory,Russian Academy of Sciences,Siberian Branch,Institute of Biophysics SB RAS)
• Esimbekova E.N. (Photobiology Laboratory,Russian Academy of Sciences,Siberian Branch,Institute of Biophysics SB RAS)

• Web of Science Core Collection
• Scopus
• Ядро РИНЦ (eLIBRARY.RU)