Сибирский федеральный университет

Тип публикации: статья из журнала

Год издания: 2014

Идентификатор DOI: 10.1007/s11094-014-1131-6

Ключевые слова: Abies sibirica, essential oil, in vitro enzymatic test systems, biological activity, alpha bisabolene, alpha terpinolene, beta bisabolene, beta pinene, borneol, bornyl acetate, camphene, caryophyllene derivative, humulene, limonene, longifolene, pinene, santene, terpenoid, terpinen 4 ol, terpinene, terpineol, terpinolene, trans caryophyllene, tricyclene, unclassified drug, Abies, Article, blood brain barrier, chemical composition, controlled study, distillation, hydrolysis, in vitro study, lipid solubility, molecular weight, nonhuman

Аннотация: The composition of essential oil isolated from Abies sibirica needles was determined. Furthermore, the compositions of various fractions obtained by distillation of the essential oil were investigated. Bornylacetate (34.21%), camphene (17.47%), and alpha-terpene (6.72%) were the major constituents of 31 detected in the essential oil. The contents of the constituents in various fractions changed during production of the essential oil depending on the distillation time. Various fractions of the essential oil were tested for biological activity that was assayed using in vitro enzymatic test systems. It was found that the biological activity of A. sibirica essential oil depended largely on the contents of the major constituents such as bornylacetate and camphene.

Журнал: PHARMACEUTICAL CHEMISTRY JOURNAL

Выпуск журнала: Vol. 48, Is. 7

Номера страниц: 456-460

ISSN журнала: 0091150X

Место издания: NEW YORK

Издатель: SPRINGER

• Polyakov N.A. (Scientific Center for Biomedical Technologies, State Research Institute of Medicinal and Aromatic Plants (VILAR))
• Dubinskaya V.A. (Scientific Center for Biomedical Technologies, State Research Institute of Medicinal and Aromatic Plants (VILAR))
• Efremov A.A. (Siberian Federal University)
• Efremov E.A. (Siberian Federal University)

• Web of Science Core Collection
• Scopus
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