Сибирский федеральный университет

Тип публикации: статья из журнала

Год издания: 2020

Идентификатор DOI: 10.1016/j.chemphyslip.2019.104851

Ключевые слова: Ferrihydrite nanoparticles, Fluidity, Laurdan, Membrane, Morphology, TMA-DPH

Аннотация: In recent years was observed an increased interest towards the use of metal nanoparticles for various biomedical applications, such as therapeutics, delivery systems or imaging. As biological membranes are the first structures with which the nanoparticles interact, it is necessary to understand better the mechanisms governing these interactions. In the present paper we aim to characterize the effect of three different ferrihydrite nanoparticles (simple or doped with cooper or cobalt) on the fluidity of model lipid membranes. First we evaluated the physicochemical properties of the nanoparticles: size and composition. Secondly, their effect on lipid membranes was also evaluated using Laurdan, TMA-DPH and DPH fluorescence. Our results can help better understand the mechanisms involved in nanoparticles and membrane interactions. © 2019 Elsevier B.V.

Журнал: Chemistry and Physics of Lipids

Выпуск журнала: Vol. 226

Номера страниц: 104851

ISSN журнала: 00093084

Издатель: Elsevier Ireland Ltd

• Chilom Claudia G. (Univ Bucharest, Fac Phys, Dept Elect Solid State & Biophys, Magurele, Romania)
• Zorila Bogdan (Horia Hulubei Natl Inst Phys & Nucl Engn, Dept Life & Environm Phys, Reactorului 30, Magurele 077125, Romania)
• Bacalum Mihaela (Horia Hulubei Natl Inst Phys & Nucl Engn, Dept Life & Environm Phys, Reactorului 30, Magurele 077125, Romania)
• Balasoiu Maria (Horia Hulubei Natl Inst Phys & Nucl Engn, Dept Nucl Phys, Magurele, Romania; Joint Inst Nucl Res, Dubna, Russia; Moscow Inst Phys & Technol, Dolgoprudnyi, Russia)
• Yaroslavtsev Roman (Siberian Fed Univ, Krasnoyarsk, Russia; SB RAS, Kirensky Inst Phys, Krasnoyarsk 660036, RussiaArticle)
• Stolyar Sergey (Siberian Fed Univ, Krasnoyarsk, Russia; SB RAS, Kirensky Inst Phys, Krasnoyarsk 660036, RussiaArticle)
• Tyutyunnicov Sergey (Joint Inst Nucl Res, Dubna, Russia)

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