Laser processing of polymer constructs from poly(3-hydroxybutyrate)

Тип публикации: статья из журнала

Год издания: 2015

Идентификатор DOI: 10.1080/09205063.2015.1082810

Ключевые слова: laser processing, biopolymers, polymer materials, poly(3-hydroxybutyrate), biocompatibility, biocompatibility, biopolymers, laser processing, poly(3-hydroxybutyrate), polymer materials, Biocompatibility, Biomechanics, Biopolymers, Bone, Cell culture, Pulsed lasers, Scaffolds (biology), Stem cells, 3t3 mouse fibroblasts, Bone marrow, Bone regeneration, Laser process, Mesenchymal stem cell, Poly-3-hydroxybutyrate, Polymer materials, Pulsed mode, Laser materials processing, poly(3 hydroxybutyric acid), artificial membrane, hydroxybutyric acid, poly-beta-hydroxybutyrate, polyester, polymer, 3T3 cell line, animal cell, Article, biocompatibility, biomechanics, bone marrow derived mesenchymal stem cell, bone regeneration, carbon dioxide laser, cell adhesion, controlled study, fibroblast, mouse, multipotent stem cell, nonhuman, priority journal, animal, artificial membrane, bone marrow cell, cell culture, cell survival, chemistry, comparative study, Cupriavidus necator, cytology, gas laser, human, mesenchymal stroma cell, metabolism, porosity, radiation response, surface property, tensile strength, tissue scaffold, ultrastructure, Wistar rat, Young modulus, Animals, Bone Marrow Cells, Cell Adhesion, Cell Survival, Cells, Cultured, Cupriavidus necator, Elastic Modulus, Humans, Hydroxybutyrates, Lasers, Gas, Membranes, Artificial, Mesenchymal Stromal Cells, Mice, NIH 3T3 Cells, Polyesters, Polymers, Porosity, Rats, Wistar, Surface Properties, Tensile Strength, Tissue Scaffolds

Аннотация: CO2 laser radiation was used to process poly(3-hydroxybutyrate) constructs - films and 3D pressed plates. Laser processing increased the biocompatibility of unperforated films treated with moderate uniform radiation, as estimated by the number and degree of adhesion of NIH 3T3 mouse fibroblast cells. The biocompatibility of perforated films modified in the pulsed mode did not change significantly. At the same time, pulsed laser processing of the 3D plates produced perforated scaffolds with improved mechanical properties and high biocompatibility with bone marrow-derived multipotent, mesenchymal stem cells, which show great promise for bone regeneration.

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Издание

Журнал: JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Выпуск журнала: Vol. 26, Is. 16

Номера страниц: 1210-1228

ISSN журнала: 09205063

Место издания: ABINGDON

Издатель: TAYLOR & FRANCIS LTD

Авторы

  • Volova T.G. (Russian Acad Sci, Siberian Branch, Inst Biophys, Krasnoyarsk 660036, Russia; Siberian Fed Univ, Sch Fundamental Biol & Biotechnol, Krasnoyarsk 660041, Russia)
  • Tarasevich A.A. (Siberian Fed Univ, Sch Engn Phys & Radio Elect, Krasnoyarsk 660041, Russia)
  • Golubev A.I. (Russian Acad Sci, Nauka Krasnoyarsk Sci Ctr, Special Design & Technol Bur, Siberian Branch, Krasnoyarsk 660049, Russia)
  • Boyandin A.N. (Russian Acad Sci, Siberian Branch, Inst Biophys, Krasnoyarsk 660036, Russia; Siberian Fed Univ, Sch Fundamental Biol & Biotechnol, Krasnoyarsk 660041, Russia)
  • Shumilova A.A. (Russian Acad Sci, Siberian Branch, Inst Biophys, Krasnoyarsk 660036, Russia; Siberian Fed Univ, Sch Fundamental Biol & Biotechnol, Krasnoyarsk 660041, Russia)
  • Nikolaeva E.D. (Russian Acad Sci, Siberian Branch, Inst Biophys, Krasnoyarsk 660036, Russia; Siberian Fed Univ, Sch Fundamental Biol & Biotechnol, Krasnoyarsk 660041, Russia)
  • Shishatskaya E.I. (Russian Acad Sci, Siberian Branch, Inst Biophys, Krasnoyarsk 660036, Russia; Siberian Fed Univ, Sch Fundamental Biol & Biotechnol, Krasnoyarsk 660041, Russia)

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