Mechanisms of influence of methicillin resistant staphylococcus aureus on functional state of neutrophilic granulocytes

Тип публикации: статья из журнала

Год издания: 2014

Ключевые слова: MRSA, MSSA, Neutrophilic granulocytes, antiinfective agent, reactive oxygen metabolite, drug effects, growth, development and aging, human, leukocyte activation, luminescence, metabolism, methicillin resistant Staphylococcus aureus, microbial sensitivity test, microbiology, multidrug resistance, neutrophil, oxygen consumption, phagocytosis, physiology, Anti-Bacterial Agents, Drug Resistance, Multiple, Bacterial, Humans, Luminescent Measurements, Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Neutrophil Activation, Neutrophils, Oxygen Consumption, Phagocytosis, Reactive Oxygen Species

Аннотация: The aim of the study was to estimate the functional activity of neutrophilic granulocytes after the contact with MSSA and MRSA. It was determined by luminol-dependent chemoluminescence with stimulation by the priming doses of MRSA and MSSA. The functional activity of neutrophilic granulocytes was shown to increase in response to either the resistant Staphylococcus aureus strains or the susceptible ones. It should be indicated that the intensity of the oxygen-dependent phagocytosis in response to MRSA was higher than that to MSSA.

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Издание

Журнал: Antibiotiki i Khimioterapiya

Выпуск журнала: Vol. 59, Is. 11-12

Номера страниц: 20-23

ISSN журнала: 02352990

Авторы

  • Kolenchukova O.A. (Research Institute of Medical Problems of the North, Krasnoyarsk, Russian Federation)
  • Sarmatova N.I. (Siberian Federal University, Krasnoyarsk, Russian Federation)

Вхождение в базы данных

  • Scopus (цитирований 1)

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