Analysis of the state-of-the-art of consulting medical care to patients with glucocorticoid-induced osteoporosis or its risk according to the data of a questionnaire survey (GLUCOST study)

Тип публикации: статья из журнала

Год издания: 2015

Идентификатор DOI: 10.17116/terarkh201587558-64

Ключевые слова: Glucocorticoid-induced osteoporosis, Glucocorticosteroids, Osteoporosis, Patient behavior, Patient knowledge, Prevention, Treatment, glucocorticoid, adult, aged, chemically induced, female, Fractures, Bone, health service, health survey, human, male, middle aged, osteoporosis, patient referral, Russian Federation, standards, statistics and numerical data, very elderly, young adult, Adult, Aged, Aged, 80 and over, Female, Fractures, Bone, Glucocorticoids, Health Services, Health Surveys, Humans, Male, Middle Aged, Osteoporosis, Referral and Consultation, Russia, Young Adult

Аннотация: Aim. To analyze the state-of-the-art of consulting medical care to Russian patients with glucocorticoid-induced osteoporosis (GCOP) or its risk. Subjects and methods. This GLUCOST study was organized and conducted by the Russian Association of Osteoporosis. A total of 1129 patients with chronic inflammatory diseases, who had been taking oral glucocorticosteroids (OGCSs) a long time (3 months or more), were examined. The patients filled out an anonymous questionnaire on their own. Whether the measures taken to diagnose, prevent, and treat GCOP complied with the main points of Russian clinical guidelines was assessed. Results. 61.8% of the patients knew that the long-term treatment of GCOP might cause osteoporosis. 48.1% of the respondents confirmed the results of bone densitometry; 78.1% of the patients reported that they had been prescribed calcium and Vitamin D supplements by their physician, but their regular intake was confirmed by only 43.4%; 25.4% of the patients had sustained one low-energy fracture or more. Treatment for GCOP was prescribed for 50.8% of the patients at high risk for fractures, but was actually received by 40.2%. Therapeutic and diagnostic measures were implemented in men less frequently than in women. When the patient was aware of GCOP, the probability that he/she would take calcium and Vitamin D supplements rose 2.7-fold (95% CI; 2.1 to 3.5; p=0.001) and that he/she would follow treatment recommendations did 3.5-fold (95% CI; 2.3 to 5.3; p=0.001). Bone densitometry increased the prescription rate for antiosteoporotic medication and patient compliance. Conclusion. According to the data of Russia's large-scale GLUCOST survey, every four patients with chronic inflammatory disease who are on long-term OGCS therapy have one low-energy fracture or more. Due to inadequate counseling, the patients are little aware of their health and do not get the care required to prevent the disease. Less than 50% of patients who have GCOP and a high risk for fractures undergo examination and necessary treatment aimed at preventing fractures.

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Издание

Журнал: Terapevticheskii Arkhiv

Выпуск журнала: Vol. 87, Is. 5

Номера страниц: 58-64

ISSN журнала: 00403660

Авторы

  • Baranova I.A. (Department of Hospital Therapy, Faculty of Pediatrics, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow, Russian Federation)
  • Ershova O.B. (Department of Therapy, Institute of Postgraduate Education, Yaroslavl State Medical Academy, Ministry of Health of Russia, Yaroslavl, Russian Federation)
  • Anaev E.Kh. (Laboratory of Noninvasive Diagnostic Methods, Research Institute of Pulmonary Medicine, Federal Biomedical Agency of Russia, Moscow, Russian Federation)
  • Anokhina T.N. (City Polyclinic Two Hundred and Twenty, Moscow Healthcare Department, Moscow, Russian Federation)
  • Anoshenkova O.N. (Tomsk Polyclinic Six, Tomsk, Russian Federation)
  • Batyn S.Z. (Laboratory of Intensive Care and Respiratory Failure, Research Institute of Pulmonary Medicine, Federal Biomedical Agency of Russia, Moscow, Russian Federation)
  • Belyaeva E.A. (Unit of Rheumatology, Tula Regional Clinical Hospital, Tula, Russian Federation)
  • Bolshakova T.Yu. (Internal Medicine Department One, Faculty of Therapeutics, Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia, Krasnoyarsk, Russian Federation)
  • Volkorezov I.A. (Rheumatology Center, Lipetsk Town Polyclinic Seven, Lipetsk, Russian Federation)
  • Eliseeva L.N. (Department of Faculty Therapy, Kuban State Medical University, Ministry of Health of Russia, Krasnodar, Russian Federation)
  • Kashnazarova E.V. (Unit of Pulmonary Diseases, City Clinical Hospital Fifty-Seven, Moscow Healthcare Department, Moscow, Russian Federation)
  • Kinyaikin M.F. (Department of Hospital Therapy with Course of Phthisiopulmonology, Pacific State Medical University, Ministry of Health of Russia, Vladivostok, Russian Federation)
  • Kirpikova M.N. (Department of Therapy and General Medical Practice, Institute of Postgraduate Education, Ivanovo State Medical Academy, Ministry of Health of Russia, Ivanovo, Russian Federation)
  • Klyuchnikova E.P. (Krasnoyarsk Territorial Clinical Hospital, Krasnoyarsk, Russian Federation)
  • Korolev M.A. (Research Institute of Clinical and Experimental Lymphology, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russian Federation)
  • Kuneevskaya I.V. (Allergology Unit, City Clinical Hospital Fifty-Seven, Moscow Healthcare Department, Moscow, Russian Federation)
  • Masneva L.V. (Rheumatology Unit, Saint Ioasaf Belgorod Regional Clinical Hospital, Belgorod, Russian Federation)
  • Muradyants A.A. (Academician A.I. Nesterov Department of Faculty Therapy, Faculty of Therapeutics, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow, Russian Federation)
  • Otteva E.N. (Rheumatology Center, Prof. S.I. Sergeev Territorial Clinical Hospital One, Ministry of Health of the Khabarovsk Territory, Khabarovsk, Russian Federation)
  • Petrachkova T.N. (Irkutsk Regional Clinical Consulting and Diagnostic Center, Irkutsk, Russian Federation)
  • Peshekhonova L.K. (Rheumatology Unit, Railway Clinical Hospital at the Voronezh-1 Station, OAO RZhD, Voronezh, Russian Federation)
  • Povzun A.S. (I.I. Dzhanelidze Saint Petersburg Research Institute of Emergency Care, Saint Petersburg, Russian Federation)
  • Raskina T.A. (Department of Internal Medicine Propedeutics, Faculty of Therapeutics, Kemerovo State Medical Academy, Ministry of Health of Russia, Kemerovo, Russian Federation)
  • Smirnova M.L. (Vologda Regional Clinical Hospital, Vologda, Russian Federation)
  • Toroptsova N.V. (Laboratory of Osteoporosis, V.A. Nasonova Research Institute of Rheumatology, Russian Academy of Sciences, Moscow, Russian Federation)
  • Khasanova R.B. (Hospital Therapy Department Two, Acad. E.A. Wagner Perm State Medical Academy, Ministry of Health of Russia, Perm, Russian Federation)
  • Shamsutdinova N.G. (Department of Hospital Therapy, Kazan State Medical University, Ministry of Health of Russia, Kazan, Russian Federation)
  • Shaporova N.L. (Faculty of Postgraduate Education, Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia, Saint Petersburg, Russian Federation)
  • Shitova N.S. (Department of Family Medicine, Northern State Medical University, Ministry of Health of Russia, Saint Petersburg, Russian Federation)
  • Shkireeva S.Yu. (Outpatient Consulting Unit, Saint Petersburg Clinical Rheumatology Hospital Twenty-Five, Saint Petersburg, Russian Federation)
  • Shostak N.A. (Academician A.I. Nesterov Department of Faculty Therapy, Faculty of Therapeutics, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow, Russian Federation)
  • Lesnyak O.M. (Department of Family Medicine, I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia, Saint Petersburg, Russian Federation)

Вхождение в базы данных

  • Scopus (цитирований 4)

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